Liver Damage

A First in Class Product that can act as a “Platform” Applicable to Multiple Diseases

ImmCelz® Activity in vivo
Associated with Tolerogenic Loop

RLiver failure significant unmet medical need
Transplant only option
Majority of liver failures caused by cirrhosis (scar tissue), associated with altered immune response locally
Activation of stellate cells is dependent on immune cells
Question was whether ImmCelz® had activity in established model (carbon tetrachloride)