12 mice where used per group. ImmCelz® was addadministered to mice 14 days after last collagen injection. Control ( diamond ) mice had rapid onset of disease. 100,000 inactive ImmCelz® cells (square). Administration of 100,000 active ImmCelz® cells (X) resulted in disease protection. Depletion of T regulatory cells by removal of CD25 positive cells resulted in negation of protection (triangle).